Does HPV have to be vaccinated? What should I do with all these vaccines?

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Must the HPV vaccine be hit? Which one should I play with such a variety of vaccines?

This article is from WeChat official account: fruit shell (ID:Guokr42), author: Li Dong Zeng, window tapping rain, pink er, fish in algae, Li Shen, head photo source: UNsplash

There are so many questions about the HPV vaccine that every time we publish a related article, we are very enthusiastic and very positive to ask our own questions in the comments. So today, we answer some representative, high-pitched questions.

Is HPV really harmful? Must I have a vaccine?

The full name of HPV is human papillomavirus, which is mainly transmitted through sexual contact (including oral sex). Most people will contract HPV shortly after sex begins.

There are many genotypes of HPV, not all of them, but at least 14 of them can cause cancer. The study suggests that more than 90% of cervical cancer is associated with persistent high-risk HPV infection.

Cervical cancer is the fourth most common cancer in women in the world and the second most common cancer in underdeveloped regions. According to the World Health Organization (WHO), there are about 570000 new cases of cervical cancer worldwide in 2018. It is estimated that more than three hundred thousand people die of cervical cancer each year, more than 85% of which occur in less developed areas.

Therefore, the World Health Organization recommends the rational use of vaccines that protect HPV.

What is the difference between the HPV vaccines? Did you have one? what else do you have to do?

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HPV vaccine 丨sipictures.com

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For those who have previously been vaccinated with bivalent or tetravalent vaccines, it is also possible for those who wish to receive another nine-valent vaccine to get better protection if conditions permit, but it is recommended to re-vaccinate at an interval of more than 12 months. If you are in the middle of a vaccination, it is not recommended to change the vaccine during the vaccination.

What is the age of application for all types of vaccines? How do you determine your age?

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But theoretically and realistically, vaccination is still protective for women beyond the recommended age, and it makes more sense for women who have passed the recommended age but have not yet started having sex.

So many people asked, how is the age of vaccination determined? Why is there sometimes a difference between China and other countries and regions?

In fact, vaccines are a special type of medicine, and there are strict systems and processes in management. It is also important to ensure safety while maximizing its role. According to the current "Administrative Measures for Drug Registration", imported vaccines must be clinically tested before they are approved for marketing in China.

Figure Pixabay

Therefore, the reason why the vaccine has such an age limit is largely because the safety and efficacy report of vaccination for other age groups in the local population is still not perfect. In other words, even if it is more useful than the recommended age, more research and data are needed to support this result.

In fact, vaccine companies are actively collecting data to expand the vaccination population and try to get more people to get HPV vaccine.

How to choose the vaccine that suits you?

To prevent the three HPV genotypes with the highest positive rate, the nine-valent vaccine is more suitable for adolescent women in China.

A nine-valent vaccine can be given if the age is right and the financial situation permits. But if the economic situation does not allow or is over 26 years old, it is better to play the second or fourth price first.

In addition, vaccines also have the best age. Given the high risk of HPV infection once you have sex and the time it takes to reach the best level of antibody in your body after vaccination, the best time for all three vaccines should be a year before the first sexual act. Of course, this is the best age to vaccinate, not to say it is useless without vaccination at this time.

If you choose to vaccinate in Hong Kong, Taiwan, etc., it is recommended to choose a regular vaccination unit, assess your physical condition before vaccination, and provide good insurance for this vaccination. After the vaccination, the vaccination record and the contact information of the vaccination hospital should be kept, and it is not recommended to immediately enter the game after vaccination to ensure the successful completion of the vaccination.

Where can I get a vaccine? How to make an appointment?

Vaccination is mainly carried out in community hospitals and community health service centers, which is the usual child immunization clinic.

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If necessary, most places can dial the 12320 health hotline from all over the country for the latest information, or book a registration platform locally for enquiries. If the local CDC center, the health department has an official account and so on, you can also check it out on the local registration platform, and if you have a local CDC center, the health department has an official account. You can also pay attention to the relevant information.

What preparations do I need to do before vaccination? Is there a check that must be done?

Some vaccination agencies will provide HPV testing and TCT testing. In fact, there is no need for HPV and HIV tests before HPV vaccination, because even those who are HPV and HIV-positive should be vaccinated against HPV. Even if you have had cervical lesions and genital warts, it is recommended to be vaccinated after treatment. HPV vaccination can reduce the recurrence rate of the disease after the infection or the resulting cervical lesions are cured.

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For the post-inoculation protection period, it is known that antibodies can be protected for at least 10 years after inoculation of bivalent and tetravalent vaccines. Because of the late market time, the nine-valent vaccine is still relatively short, but the available data show that the antibody can be protected for at least 5 years, and the data model shows that the protection period may reach more than 50 years, which requires further practical data to confirm.

Preparation pregnancy, lactation period can play?

Pregnant women should avoid vaccination with HPV because research is not sufficient. If you are pregnant during the vaccination, you do not need to terminate the pregnancy, as long as you delay the vaccination to the time of delivery and then vaccinate. Women during pregnancy are also advised to wait until the end of the gestation period. The current data does not find that women who are unintended during vaccination have a vaccine-related adverse outcome.

HPV vaccination should be avoided during pregnancy? Pixabay

For lactating women, the views of different institutions vary. The World Health Organization (WHO) believes that although breastfeeding is not a contraindication to HPV vaccination, safety data is limited and caution should be exercised during lactation. The American College of Obstetricians and Gynecologists is more active in thinking that lactating women who have not been vaccinated with HPV in the past can be vaccinated and should be vaccinated. Lactating women are not recommended for HPV vaccine in the Mainland of China.

Do men need to take HPV vaccine?

The three vaccines did not approve male vaccination in China. The bivalent vaccine is against cervical cancer caused by HPV16 and HPV18. Although men may carry both viruses, they are not pathogenic to men, so men do not need to be vaccinated. Men can choose to use condoms to avoid spreading the two subtypes of the virus to their partner.

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What are the common side effects of HPV vaccines?

Adverse reactions to HPV vaccines are usually mild and have a short duration. The most common adverse reactions are mainly local pain and redness. The local response of the nine-valent vaccine is more common than the four-valent vaccine. It can be said that most people who inoculate the nine-valent vaccine will have local symptoms.

As for systemic adverse reactions, the most common is fever, followed by headache, nausea and fatigue. However, the symptoms of adverse reactions in most people will not last longer than 4 to 5 days, and no special treatment is needed. Other serious adverse reactions such as neurological complications and vascular embolism have not been confirmed by the World Health Organization.

Some studies followed up the vaccinated population for 8 years and found no long-term adverse reactions to the HPV vaccine.

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Is the vaccine really safe?

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There are often rumors about the health risks of the HPV vaccine, claiming that a large number of victims have serious consequences such as "clogging blood vessels", "epilepsy", "miscarriage of pregnant women" after vaccination. But so far, no evidence of increased risk of serious adverse consequences from the HPV vaccine has been found.

After the HPV vaccination, there were cases of adverse events and deaths were reported. However, this is a case, and there are many confounding factors such as drug abuse, infection, and underlying diseases in these cases. It is therefore unfounded to claim that the vaccine is “extremely dangerous”.

Many people asked about a widely circulated online article, "the nightmare of falsely claiming that the HPV vaccine against cervical cancer" is finally coming: us courts have begun to hear the terrible corruption of the HPV vaccine approval agencies and companies. The English version of the article originally came from the American Child Health Defense website, (childrens health defense.org, and if you look closely at it, it's a site that advocates vaccine conspiracy theories, not just HPV vaccines, but also hepatitis B vaccines. The flu vaccine, among other things, has been charged.

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On the official website, you can't find such a message. The US CDC and FDA mentioned in the article were bought by companies, but in fact, HPV vaccines have been listed in many countries around the world, and many countries have incorporated them into national immunization programs. Numerous international clinical trials have evaluated the efficacy, safety, and duration of protection of HPV vaccines, and HPV vaccines are generally considered safe and effective.

The elders at home are over 45 years old, and several vaccines can't be played. What should I do?

If there are female elders over the age of 45 in the family, the three vaccines are more than the recommended age and cannot be vaccinated. Is it impossible to prevent cervical cancer?

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This is even more important for older women who cannot be vaccinated. Regular screening can lead to the discovery of precancerous lesions at a more manageable stage, thereby reducing the risk of disease.

Reference materials:

Https://www.who.int/news-room/fact-sheets/detail/human-papillomavirus-(hpv)-and-cervical-cancer

This article is from WeChat official account: fruit shell (ID:Guokr42), author: Li Dong Zeng, window tapping rain, pink er, fish in algae, Li Shen, head photo source: UNsplash

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